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Developers today face significant challenges when building highly resilient, secure, and scalable applications for a global customer base. Whether modernizing existing apps or building new cloud native apps, developers must make architecture and design decisions across a variety of technology choices. As business demands change rapidly, developers are asked to do more than ever. Discover how these events can be processed asynchronously and stored for reporting and analysis. This session will cover how to build a tiered, robust web application using Kubernetes and Oracle databases.
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Tissue macrophages, including the microglia in the brain, act as critical sentinels to defend us against infection. Consequently, pathogens such as HIV have developed ways of circumventing the defensive functions of macrophages in order to establish chronic infection. Moreover, their persistence in macrophages appears to generate chronic inflammatory reactions, that may lead to the dysfunction of neighbouring cells, such as neurons, and result in neurocognitive disorders. In order to dissect the molecular pathways involved in these processes, we have developed human iPS cell-derived tissue models for macrophages, microglia and neurons, and use high-efficiency Cas9-based gene editing methods to investigate the contribution of individual components. Her team generate, edit, curate and differentiate dozens of iPS lines as part of multi-centre collaborations to investigate the pathogenesis of neurodegenerative and related disorders.
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Its aims are to strengthen this fascinating and scientific hobby as well as the international DX movement for better understanding and friendship among nations. Anyone can become a member of WORLDWIDE DX CLUB regardless of nationality and political belief. WORLDWIDE DX CLUB does not claim to be the biggest or best DX club in the world. Since WORLDWIDE DX CLUB is the "International Department" of ARBEITSGEMEINSCHAFT DX e.
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